Muskan Floren, PhD

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Biomedical Scientist -- Cancer Biology

Publications

Pascetti, E., Floren, M., Fernandes, T. D. S., Anastasio, C., Doyle, L., & Gillette, J. (2025). Tetraspanin CD82 regulates transforming growth factor-β signaling in hematopoietic stem and progenitor cells. Molecular Biology of the Cell, 36(7), br19.

Bibikova, E., Parsa, S., Floren, M., Law, B., Clevenger, T., Cheung, J., … & Mortlock, A. (2025). Molecular profiling identifies CD49d and CD79b as predictive markers for acquired acalabrutinib resistance in patients with chronic lymphocytic leukemia. Hematological oncology, 43(1), e70008.

Shah, R., Wander, H., Hsueh, M., Floren, M., Liu, W., Cheung, P., … & Auclair, D. (2024). Multiplexed flow cytometry based immunophenotyping paired with functional ex vivo (MFLEX) drug profiling informs potential efficacy of therapeutic agents in acute myeloid leukemia. Cancer Research, 84(6_Supplement), 3904-3904.

Wu, X., Islam, S., Oien, D.B., Tokheim, C., Beacom, A., Aryal, N., Hsueh, M., Floren, M., Ross-Thriepland, D., Barrell, D. and McDermott, U. (2023). A Multi-Modal Analysis of Acquired Resistance to Acalabrutinib and Pirtobrutinib Provides Potential Strategies to Augment Treatment Outcome with BTKi Drugs. Blood, 142, 1452.

Pascetti, E.M., Restrepo-Cruz, S., Floren, M., Saito-Reis, C.A., Balise, V.D. and Gillette, J.M., 2021. Tetraspanin CD82 Regulates Hematopoietic Stem and Progenitor Cell Quiescence and Regeneration. Blood, 138(Supplement 1), pp.3264-3264.

Muskan Floren, Jennifer M. Gillette. 2021. “Acute myeloid leukemia: Therapy resistance and a potential role for tetraspanin membrane scaffolds”, The International Journal of Biochemistry & Cell Biology. (full paper)

Floren, M., S. Restrepo Cruz, C. M. Termini, K. D. Marjon, K. A. Lidke, and J. M. Gillette. 2020. “Tetraspanin CD82 drives acute myeloid leukemia chemoresistance by modulating protein kinase C alpha and beta1 integrin activation”, Oncogene. (full paper)

Saito-Reis, C. A., K. D. Marjon, E. M. Pascetti, M. Floren, and J. M. Gillette. 2018. “The tetraspanin CD82 regulates bone marrow homing and engraftment of hematopoietic stem and progenitor cells”, Molecular Biology of the Cell, 29: 2946-58.

O’Donnell, P., J. Shyu, J. Ferguson, K. Demartin, T. May, D. Jensen, M. Celeri, T. Rehage, L. Corona, R. Current, S. Joshi, Y. Wu, M. Floren, and S. Soviero. 2016. “A Real-time PCR Assay for the Detection of EGFR Mutations in FFPE Tissue and Plasma Samples of NSCLC Patients”, Journal of Clinical Oncology, 34: e23251-e51.

Turk-Kubo, K. A., M. Karamchandani, D. G. Capone, and J. P. Zehr. 2014. “The paradox of marine heterotrophic nitrogen fixation: abundances of heterotrophic diazotrophs do not account for nitrogen fixation rates in the Eastern Tropical South Pacific”, Environmental Microbiology, 16: 3095-114.

Oral Presentations

Poster Presentations